Life-stage-associated remodelling of lipid metabolism regulation in Atlantic salmon

Daily Rhythms in Expression of Genes of Hepatic Lipid Metabolism in Atlantic Salmon (Salmo salar L.)

In mammals, several genes involved in liver lipid and cholesterol homeostasis are rhythmically expressed with expression shown to be regulated by clock genes via Rev-erb 1α. In order to elucidate clock gene regulation of genes involved in lipid metabolism in Atlantic salmon (Salmo salar L.), the orphan nuclear receptor Rev-erb 1α was cloned and 24 h expression of clock genes, transcription fact...

Regulation of Bone Metabolism

Bone is formed through the processes of endochondral and intramembranous ossification. In endochondral ossification primary mesenchymal cells differentiate to chondrocytes and then are progressively substituted by bone, while in intramembranous ossification mesenchymal stem cells (MSCs) differentiate directly into osteoblasts to form bone. The steps of osteogenic proliferation, differentiation,...

securitization of mortality risks in life annuities

insurers have in the past few decades faced longevity risks - the risk that annuitants survive more than expected - and therefore need a new approach to manage this new risk. in this dissertation we survey methods that hedge longevity risks. these methods use securitization to manage risk, so using modern financial and insurance pricing models, especially wang transform and actuarial concepts, ...

Atlantic Salmon in Maine

Nutrigenomic Study of Lipid Metabolism in Atlantic Salmon (salmo Salar L.) - the Effects of Dietary Plant Oil Inclusions

The two dietary trials conducted in the present study (Papers I-III) used dietary rapeseed oil fed in a regression design and a full plant oil blend replacement for fish oil, respectively. The metabolic response of Atlantic salmon was examined in relation to gene expression (Paper I-III), lipid storage (Paper II and III) and fatty acid oxidation (Paper II). Furthermore, intracellular fatty acid...